PARP1 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 4A9
Isotype: IgG1
Immunogen: poly (ADP-ribose) polymerase 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 115 kDa, 89 kDa
Uniprot: P09874
Gene id: 142
Background: PARP1 (poly(ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly(ADP-ribosyl)ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:5000 - 1:30000; IHC: 1:100 - 1:1000; IF: 1:50 - 1:500
Target: PARP1
Purification: protein A+G purified
Reactivity: Human, Mouse, Rat
![]()
Clonality: Monoclonal
Clone: 4A9
Isotype: IgG1
Immunogen: poly (ADP-ribose) polymerase 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 115 kDa, 89 kDa
Uniprot: P09874
Gene id: 142
Background: PARP1 (poly(ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly(ADP-ribosyl)ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:5000 - 1:30000; IHC: 1:100 - 1:1000; IF: 1:50 - 1:500
Target: PARP1
Purification: protein A+G purified
Reactivity: Human, Mouse, Rat